Benzenebutanoic acid, 4-bromo-b-[[(1,1-dimethylethoxy)carbonyl]amino]-,(bR)- - Names and Identifiers
Benzenebutanoic acid, 4-bromo-b-[[(1,1-dimethylethoxy)carbonyl]amino]-,(bR)- - Physico-chemical Properties
Molecular Formula | C15H20BrNO4
|
Molar Mass | 358.23 |
Density | 1.370 |
Melting Point | 144-146℃ |
Boling Point | 491.9±40.0 °C(Predicted) |
pKa | 4.40±0.10(Predicted) |
Storage Condition | Room Temprature |
Benzenebutanoic acid, 4-bromo-b-[[(1,1-dimethylethoxy)carbonyl]amino]-,(bR)- - Risk and Safety
Benzenebutanoic acid, 4-bromo-b-[[(1,1-dimethylethoxy)carbonyl]amino]-,(bR)- - Introduction
Benzenebutanoic acid, 4-bromo-b-[[(1,1-dimenthylethoxy) carbonyl]amino]-,(bR)-, also known as Boc-(R)-4-bromo-phenylalanine, is an organic compound. The following is a description of the properties, uses, preparation and safety information of the compound:
Nature:
-chemical formula: C16H20BrNO4
-Molecular weight: 363.24g/mol
-Appearance: White Crystal
-Melting point: About 76-79 ° C
-Solubility: Soluble in organic solvents such as ether and dimethyl sulfoxide, slightly soluble in water.
Use:
- Benzenebutanoic acid, 4-bromo-b-[[(1,1-dimenthylethoxy) carbonyl]amino]-,(bR)-is an amino acid derivative, it is often used in organic synthesis as a reagent or starting material.
-It can be used to synthesize peptides, proteins, fluorescent labeling agents and other compounds.
Method:
- Benzenebutanoic acid, 4-bromo-b-[[(1,1-dimenthylethoxy) carbonyl]amino]-,(bR)-can be synthesized by the following steps:
1) First, 4-bromophenylbutyric acid is reacted with a BOC protecting group through an acylation reaction to obtain BOC-(R)-4-bromo-phenylalanine.
2) Then, BOC-(R)-4-bromo-phenylalanine activated by reaction reacts with aminoacetal or aminoketal under alkaline conditions to obtain Benzenebutanoic acid, 4-bromo-b-[[(1,1-dimenthylethoxy) carbonyl]amino]-,(bR)-.
Safety Information:
- Benzenebutanoic acid, 4-bromo-b-[[(1,1-dimenthylethoxy) carbonyl]amino]-,(bR)-has certain irritation and corrosiveness, wear appropriate protective gloves and eye protection.
-Avoid contact with organic solvents or combustibles during use or storage to prevent fire or explosion.
-The compound should be kept away from children and stored, handled and disposed of properly.
Last Update:2024-04-10 22:29:15